Application
Western blot analysis of Neurotensin expression in Jurkat (A), HT-1080 (B), Caki-1 (C), IMR-32 (D) and K-562 (E) whole cell lysates.Application
Western blot analysis of Neurotensin expression in EOC 20 (A) and c4 (B) whole cell lysates.Application
Western blot analysis of Neurotensin expression in HT-1080 (A), MIA PaCa-2 (B) and Caki-1 (C) whole cell lysates.| Product Name | Neurotensin Antibody (FL-170) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The Neurotensin precursor (also known as Pro-NT/NMN) is a 170 amino acid protein that is cleaved at carboxy terminal dibasic residues by prohormone convertase to generate three processed peptides, designated Neurotensin (NT), Neuromedin N (also known as NMN) and large Neuromedin N (also known as NMN-125). The Neurotensin precursor is processed in the central nervous system and in the intestine to generate the 13 amino acid processed Neurotensin peptide. While the processed Neurotensin peptide functions as a neurotransmitter to modulate dopaminergic signaling pathways in the brain, it acts as a parahormone that may contribute to the growth of human colon cancers in the gut. The processed peptides Neurotensin and Neuromedin N bind to the G-protein coupled Neurotensin receptor (NTR), resulting in the hydrolysis of phosphatidylinositols and the mobilization of calcium. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Neurotensin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-170 representing full length Neurotensin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-170 representing full length Neurotensin of human origin |
| Entrez Gene | 4922 |
|---|
Application
Western blot analysis of Neurotensin expression in Jurkat (A), HT-1080 (B), Caki-1 (C), IMR-32 (D) and K-562 (E) whole cell lysates.
Application
Western blot analysis of Neurotensin expression in EOC 20 (A) and c4 (B) whole cell lysates.
Application
Western blot analysis of Neurotensin expression in HT-1080 (A), MIA PaCa-2 (B) and Caki-1 (C) whole cell lysates.| Application Notes | recommended for detection of Neurotensin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
