Application
Western blot analysis of GGT5 expression in non-transfected: (A) and human GGT5 transfected: (B) 293 whole cell lysates.Application
Western blot analysis of GGT5 expression in non-transfected: (A) and human GGT5 transfected: (B) 293T whole cell lysates.| Product Name | GGT5 Antibody (H-235) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 161-395 mapping to an internal region of GGT5 human origin |
| Modification Notes | g-glutamyltranspeptidase (GGT) acts as a glutathionase and catalyzes the transfer of the glutamyl moiety of Glutathione to a variety of amino acids and dipeptide acceptors. This enzyme is located on the outer surface of the cell membrane and is widely distributed in mammalian tissues involved in absorption and secretion. In humans, hepatic GGT activity is elevated in some liver diseases. GGT1 is released into the bloodstream after liver damage and an elevated level of the enzyme may be a useful early sign of hepatocellular carcinoma. GGT5 converts Leukotriene C4 to Leukotriene D4; it does not, however, convert synthetic substrates that are commonly used to assay GGT. In human serum and tissues there is a marked heterogeneity in GGT, but this heterogeneity can be attributed to different glycosylation of the same peptide rather than to the products of different genes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of GGT5 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 161-395 mapping to an internal region of GGT5 human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 161-395 mapping to an internal region of GGT5 human origin |
| Entrez Gene | 2687 |
|---|
Application
Western blot analysis of GGT5 expression in non-transfected: (A) and human GGT5 transfected: (B) 293 whole cell lysates.
Application
Western blot analysis of GGT5 expression in non-transfected: (A) and human GGT5 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of GGT5 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
