Application
Western blot analysis of CB2 expression in HL-60 (A) and Jurkat (B) whole cell lysates.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing cytoplasmic staining of surface epithelial cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of human recombinant CB2 fusion protein.| Product Name | CB2 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The cannabinoid receptors (CB1 and CB2) are G-protein coupled receptors that inhibit adenylate cyclase activity in response to psychoactive cannabinoids (1-3). CB1 is expressed in brain tissue and, in low levels, in testis (1,4). CB2 has been shown to be expressed only by cells of the immune system, specifically by HL-60 cells (5). The cannabinoid receptors mediate most of the cannabinoid-induced responses in a dose-dependent, stereoselective manner (1,3). This response system is thought to be involved in specific brain functions, such as nociception, control of movement, memory, and neuroendocrine regulation as well as having a possible role in brain development (6). In addition, CB1 may mediate the addictive behavior involved with the use of psychoactive cannabinoids, such as THC in marijuana (3,7,8). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of CB2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 301-360 mapping at the C-terminus of CB2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 301-360 mapping at the C-terminus of CB2 of human origin |
| Entrez Gene | 1269 |
|---|
Application
Western blot analysis of CB2 expression in HL-60 (A) and Jurkat (B) whole cell lysates.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human oral mucosa tissue showing cytoplasmic staining of surface epithelial cells at low (A) and high (B) magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of human recombinant CB2 fusion protein.| Application Notes | recommended for detection of CB2 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
