Application
Western blot analysis of TRAF5 expression in non-transfected: (A) and mouse TRAF5 transfected: (B) 293T whole cell lysates.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells (low and high magni?fication). Kindly provided by The Swedish Human Protein Atlas (HPA) program.Application
Western blot analysis of TRAF5 expression in Jurkat (A) and CCRF-HSB-2 (B) whole cell lysates.Application
Western blot analysis of His-tagged human recombinant TRAF5.| Product Name | TRAF5 Antibody (H-257) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TRAF5 is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins are associated with, and mediate signal transduction from members of the TNF receptor superfamily. TRAF5 is one of the components of a complex associated with the CD40 cytoplasmic domain, which mediates TNF induced NF-kappa B activation and protection from cell death. TRAF5 influences signaling events by other receptors including CD27, CD30, and lymphotoxin-beta receptor. TRAF5 plays a role in osteoclastogenesis. Two alternatively spliced transcript variants encoding the same protein have been reported. The tumor necrosis factor (TNF) receptor superfamily is composed of several type I integral membrane glycoproteins that exhibit homology in their cystine-rich extracellular domains. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of TRAF5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine and bovine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-257 mapping at the N-terminus of TRAF5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-257 mapping at the N-terminus of TRAF5 of human origin |
| Entrez Gene | 7188 |
|---|
Application
Western blot analysis of TRAF5 expression in non-transfected: (A) and mouse TRAF5 transfected: (B) 293T whole cell lysates.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human stomach tissue showing cytoplasmic staining of glandular cells (low and high magni?fication). Kindly provided by The Swedish Human Protein Atlas (HPA) program.
Application
Western blot analysis of TRAF5 expression in Jurkat (A) and CCRF-HSB-2 (B) whole cell lysates.
Application
Western blot analysis of His-tagged human recombinant TRAF5.| Application Notes | recommended for detection of TRAF5 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine and bovine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
