Application
Western blot analysis of ACTR-IIB expression in Hep G2 whole cell lysate.Application
Western blot analysis of ACTR-IIB expression in NIH/3T3 whole cell lysate.| Product Name | ACTR-IIB Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 108-177 mapping near the N-terminus of ACTR-IIB of human origin |
| Modification Notes | Members of the transforming growth factor b superfamily bind to a pair of transmembrane proteins, known as receptor types I and II, which contain serine/threonine kinases and associate to form a signaling complex (1). Activin has been shown to bind a heteromeric noncovalent complex, which consists of a type I receptor, ACTR-IA (also designated ACVRI and ALK-2) or ACTR-IB (also designated ALK-4 and SKR2), and a type II receptor, ACTR-IIA (also designated ACVR2A) or ACTR-IIB (also designated ACVR2B) (1-6). Both receptor types are highly expressed in brain (5). The activin receptor family members are thought to mediate distinct effects on gene expression, cell differentiation, and morpho- genesis in a dose dependent fashion (5,6). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ACTR-IIB of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 108-177 mapping near the N-terminus of ACTR-IIB of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 108-177 mapping near the N-terminus of ACTR-IIB of human origin |
| Entrez Gene | 93 |
|---|
Application
Western blot analysis of ACTR-IIB expression in Hep G2 whole cell lysate.
Application
Western blot analysis of ACTR-IIB expression in NIH/3T3 whole cell lysate.| Application Notes | recommended for detection of ACTR-IIB of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
