Application
Western blot analysis of PSR expression in non-transfected: (A) and mouse PSR transfected: (B) 293T whole cell lysates.Application
Western blot analysis of PSR expression in non-transfected: (A) and human PSR transfected: (B) 293T whole cell lysates.Application
Western blot analysis of PSR expression in Caki-1 (A), THP-1 (B), HT-1080 (C), HeLa (D), A549 (E), NIH/3T3 (F) and 3611-RF (G) whole cell lysates.| Product Name | PSR Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Cells undergoing apoptosis lose the asymmetry of plasma membrane phospholipids, and phosphatidylserine is exposed on the outer surface of the membrane. The phosphatidylserine receptor (PSR) specifically recognizes phosphatidylserine and this binding triggers the phagocytosis of apoptotic cells by either macrophages or dendritic cells. PSR is expressed on the surface of macrophages, fibroblasts, and epithelial cells, and it has been detected in high levels in heart, skeletal muscle, and kidney tissues and is extensively glycosylated. The mammalian phosphatidylserine receptor displays significant homology to Caenorhabditis elegans and Drosophila melanogaster proteins, which suggests that PSR has been conserved throughout phylogeny. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PSR of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 of PSR of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 of PSR of human origin |
| Entrez Gene | 23210 |
|---|
Application
Western blot analysis of PSR expression in non-transfected: (A) and mouse PSR transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of PSR expression in non-transfected: (A) and human PSR transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of PSR expression in Caki-1 (A), THP-1 (B), HT-1080 (C), HeLa (D), A549 (E), NIH/3T3 (F) and 3611-RF (G) whole cell lysates.| Application Notes | recommended for detection of PSR of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
