Application
Western blot analysis of BMAL2 expression in non-transfected: (A) and human BMAL2 transfected: (B) 293 whole cell lysates and Hep G2 nuclear extract (C).Application
Western blot analysis of BMAL2 expression in non-transfected: (A) and human BMAL2 transfected: (B) 293 whole cell lysates.| Product Name | BMAL2 Antibody (H-166) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 471-636 mapping at the C-terminus of BMAL2 of human origin |
| Modification Notes | BMAL2, also known as ARNTL2 (aryl hydrocarbon receptor nuclear translocator-like 2), MOP9, CLIF or PASD9, is a 636 amino acid protein that localizes to the nucleus and contains one bHLH (basic helix-loop-helix) domain, one PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains. Expressed at high levels in placenta and brain and at lower levels in liver, thymus, heart, lung and kidney, BMAL2 functions as a component of the circadian core oscillator, which includes a variety of proteins that work in tandem to activate the transcription of target genes. More specifically, BMAL2, when functioning as a component of the core oscillator, binds to the E-box element (3'-CACGTG-5') of target DNA, thus inducing transcription. Multiple isoforms of BMAL2 exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BMAL2 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 471-636 mapping at the C-terminus of BMAL2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 471-636 mapping at the C-terminus of BMAL2 of human origin |
| Entrez Gene | 56938 |
|---|
Application
Western blot analysis of BMAL2 expression in non-transfected: (A) and human BMAL2 transfected: (B) 293 whole cell lysates and Hep G2 nuclear extract (C).
Application
Western blot analysis of BMAL2 expression in non-transfected: (A) and human BMAL2 transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of BMAL2 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
