Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic staining of glandular cells.Application
Western blot analysis of Fes expression in HL-60 whole cell lysate.Application
Western blot analysis of Fes expression in non-transfected: (A) and human Fes transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Fes expression in non-transfected: (A) and human Fes transfected: (B) 293T whole cell lysates.Application
Western blot analysis of Fes expression in mouse heart (A) and rat heart (B) tissue extracts.| Product Name | Fes Antibody (H-65) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 758-822 mapping at the C-terminus of Fes of human origin |
| Modification Notes | Fes, a tyrosine kinase encoded by the proto-oncogene c-fes, is expressed in macrophages and is thought to be involved in the regulation of myeloid differentiation. Fes has several characteristics typical of a cytoplasmic class of protein tyrosine kinases, including an SH2 domain and autophosphorylation capabilities. Fes has been shown to associate with IL-4 and several hematopoietic cytokine receptors, as well as with BCR. Phosphorylation of BCR by Fes induces the association of BCR with the Ras guanine nucleotide exchange factor complex GRB2/Sos. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of Fes of mouse, rat and human origin by WB, IP, IF,IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 758-822 mapping at the C-terminus of Fes of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 758-822 mapping at the C-terminus of Fes of human origin |
| Entrez Gene | 2242 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human gall bladder tissue showing cytoplasmic staining of glandular cells.
Application
Western blot analysis of Fes expression in HL-60 whole cell lysate.
Application
Western blot analysis of Fes expression in non-transfected: (A) and human Fes transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Fes expression in non-transfected: (A) and human Fes transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of Fes expression in mouse heart (A) and rat heart (B) tissue extracts.| Application Notes | recommended for detection of Fes of mouse, rat and human origin by WB, IP, IF,IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
