Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human vagina tissue showing cytoplasmic staining of squamous epithelial cells.Application
Western blot analysis of S-100A10 expression in mouse brain tissue extract.| Product Name | S-100A10 Antibody (H-80) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 3-82 mapping within an internal region of S-100A10 of human origin |
| Modification Notes | The S-100 family of calcium-activated proteins interact with a range of target proteins to modulate biological signaling pathways. Numerous cancer cell lines overexpress the plasminogen receptor S-100A10 on the extracellular cell surface, where it forms a heterotetrameric complex with Annexin II, though this association is not required for plasma membrane localization or binding and activation of plasminogen. Additionally, S-100A10 acts as a cellular chaperone for hepatitis B (Hep B) virus polymerase. Hep B virus polymerase normally localizes to the cytoplasm only, though in the presence of S-100A10 a portion relocates to the nucleus, implying a role for S-100A10 and intracellular calcium in the process of viral replication. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of S-100A10 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 3-82 mapping within an internal region of S-100A10 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 3-82 mapping within an internal region of S-100A10 of human origin |
| Entrez Gene | 6281 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human vagina tissue showing cytoplasmic staining of squamous epithelial cells.
Application
Western blot analysis of S-100A10 expression in mouse brain tissue extract.| Application Notes | recommended for detection of S-100A10 of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
