epitope corresponding to amino acids 41-76 mapping near the N-terminus of TR4 of mouse origin
Modification Notes
The human TR2 orphan receptor is a member if the steroid/thyroid hormone receptor superfamily that controls a variety of processes, including growth, differentiation and development. TR2 is known to bind to regulatory elements of the erythropoietin gene, the muscle-specific aldolase A gene and the CNTF-15 gene. In addition to TR2, a related orphan receptor, TR4 has been identified. This protein forms heterodimers with TR2, which are thought to be involved in neurogenesis and germ cell development. TR2 is known to be downregulated by both p53 and ionizing radiation, and it may play a role in linking p53 to members of the steroid receptor family.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TR4 of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 41-76 mapping near the N-terminus of TR4 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 41-76 mapping near the N-terminus of TR4 of mouse origin
Western blot analysis of TR4 expression in 3T3-L1 (A) and F9 (B) whole cell lysates.
Application Notes
recommended for detection of TR4 of mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.