| Product Name | MaxiKβ Antibody (FL-191) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-191 representing full length MaxiKβ of human origin |
| Modification Notes | The KCNMB1 gene, located on chromosome 5q35.1, contains four exons and encodes the 191 amino-acid protein MaxiK∫ subunit 1 (also designated calcium-activated potassium channel ∫ subunit, BK channel ∫ subunit, Slo-∫ and KVCA∫). MaxiK∫ subunit 1 consists of two putative transmembrane domains, an extracellular loop containing three consensus sequences for N-linked glycosylation and four cysteine residues that might form disulfide bridges. One of four subunits in the MaxiK∫ family, MaxiK∫ subunit 1 is expressed predominately in smooth muscle tissue but is also found in brain, liver and lymphatic tissues. MaxiK∫ subunit 1 associates with MaxiKå to form a calcium-activated potassium channel (also designated MaxiK and BK channel) and increases the sensitivity of the MaxiKå to calcium and voltage. The å/∫1 channel is the most sensitive of all Maxi channels to calcium. MaxiK∫ plays an important role in vasoregulation by controlling the sensitivity of MaxiK channels to calcium, which leads to the proper amount of arterial relaxation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MaxiKβ of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-191 representing full length MaxiK&beta of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-191 representing full length MaxiKβ of human origin |
| Entrez Gene | 3779 |
|---|
| Application Notes | recommended for detection of MaxiKβ of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
