Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase to endosomes from the Golgi and back again. Cargo selection protein TIP47, also designated placental protein 17, is required for the transport from endosomes to the trans-Golgi network and interacts with the cytoplasmic domains of both cation-dependent and cation-independent MPRs. Another member of the peripilin family, Adipophilin (ADRP), is a protein associated with the globule surface membrane material of milk lipid globules. The phos-phoprotein Perilipin (Peri) is located on the surface of intracellular lipid droplets within adipocytes where it protects lipid storage droplets by coating them in adipocytes until they are digested by lipase. As a critical regulator of lipolysis, elevated Perilipin levels have been linked to obesity.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ADRP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of ADRP of human origin
Tissue Specificity
epitope mapping near the C-terminus of ADRP of human origin
Western blot analysis of human recombinant ADRP fusion protein.
Application
Western blot analysis of ADRP expression in 293T whole cell lysate (A) and human liver tissue extract (B).
Application Notes
recommended for detection of ADRP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.