| Product Name | Urm1 Antibody (H-78) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Ubiquitin (Ub) is among the most phylogenetically conserved proteins known. The primary function of this small, 76 amino acid protein is to clear abnormal, foreign and improperly folded proteins by targeting them for degradation by the 26S proteosome. Many ubiquitin-like proteins function as post-translational protein modifiers, such as members of the SUMO protein family, however some ubiquitin-like proteins regulate protein-protein interactions and cell cycle events, thereby functioning outside of the traditional ubiquitination pathway. Urm1 (Ubiquitin-related modifier 1 homolog) is a 101 amino acid protein that primarily functions in the post-translational modification of proteins by way of the urmylation pathway. In studies with Saccharomyces cerevisiae, it has been found that Urm1 covalently binds to its E1 activating enzyme, Uba4p, to conjugate alkyl hydroperoxide reductase (Ahp1). It is hypothesized that this complex may then play a role in the oxidative-stress response in mammals. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Urm1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 24-101 mapping at the C-terminus of Urm1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 24-101 mapping at the C-terminus of Urm1 of human origin |
| Entrez Gene | 81605 |
|---|
| Application Notes | recommended for detection of Urm1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
