| Product Name | HSPA6 Antibody (H-50) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 591-640 mapping near the C-terminus of HSPA6 of human origin |
| Modification Notes | The heat shock proteins (HSPs) comprise a group of highly conserved, abundantly expressed proteins with diverse functions, including the assembly and sequestering of multi-protein complexes, the transportation of nascent polypeptide chains across cellular membranes and the regulation of protein folding. HSPA6 (heat shock 70kDa protein 6), also known as HSP70B, is a 643 amino acid protein that belongs to the HSP family and, like other HSP proteins, mediates protein folding within the cytosol, as well as within other organelles throughout the cell. The gene encoding HSPA6 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HSPA6 of human origin by WB, IP, IF and ELISA non cross-reactive with other HSPA family members also reactive with additional species, including equine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 591-640 mapping near the C-terminus of HSPA6 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 591-640 mapping near the C-terminus of HSPA6 of human origin |
| Entrez Gene | 3310 |
|---|
| Application Notes | recommended for detection of HSPA6 of human origin by WB, IP, IF and ELISA non cross-reactive with other HSPA family members also reactive with additional species, including equine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
