WD-repeats are motifs that are found in a variety of proteins and are characterized by a conserved core of 40-60 amino acids that commonly form a tertiary propeller structure. While proteins that contain WD-repeats participate in a wide range of cellular functions, they are generally involved in regulatory mechanisms concerning chromatin assembly, cell cycle control, signal transduction, RNA processing, apoptosis and vesicular trafficking. WDR78 (WD repeat domain 78) is an 848 amino acid protein that contains six WD repeats and exists as three alternatively spliced isoforms. The gene encoding WDR78 maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of WDR78 isoforms of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other WDR family members
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of WDR78 of human origin
Tissue Specificity
epitope mapping within an internal region of WDR78 of human origin