| Product Name | CPSF7 Antibody (H-53) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | 3' ends of eukaryotic mRNAs can undergo processing events that include endonucleolytic cleavage and polyadenylation. Cleavage and polyadenylation specificity factors (CPSF) mediate 3' cleavage of the transcript and subsequent polyadenylation. CPSF7 (cleavage and polyadenylation specific factor 7), also known as MGC9315, FLJ12529 or FLJ39024, is a 471 amino acid nuclear protein belonging to the RRM CPSF6/7 family. As a result of alternative splicing events, two CPSF7 isoforms exist. CPSF7 contains one RRM (RNA recognition motif) domain, and is encoded by a gene which maps to to human chromosome 11q12.2. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CPSF7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 185-237 mapping within an internal region of CPSF7 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 185-237 mapping within an internal region of CPSF7 of human origin |
| Entrez Gene | 79869 |
|---|
| Application Notes | recommended for detection of CPSF7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
