GalNAcT-2 (chondroitin sulfate N-acetylgalactosaminyltransferase 2), also known as CSGALNACT2 or CHGN2, is a 542 amino acid single-pass type II membrane protein belonging to the chondroitin N-acetylgalactosaminyltransferase family. Localizing to Golgi apparatus, GalNAcT-2 is ubiquitously expressed with high levels found in small intestine, leukocytes, and spleen. GalNAcT-2 plays an essential role in elongation of chondroitin chains by adding GalNAc to the core tetrasaccharide linker. GalNAcT-22 also transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid. GalNAcT-2 exists as two alternatively spliced isoforms.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of GalNAcT-2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with &beta-1,4-GalNAc-T also reactive with additional species, including equine, canine, bovine, porcine and avian
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the N-terminus of GalNAcT-2 of human origin
Tissue Specificity
epitope mapping near the N-terminus of GalNAcT-2 of human origin
Western blot analysis of GalNAcT-2 expression in non-transfected: (A) and mouse GalNAcT-2 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of GalNAcT-2 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with &beta-1,4-GalNAc-T also reactive with additional species, including equine, canine, bovine, porcine and avian
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.