KLRG2 (killer cell lectin-like receptor subfamily G member 2), also known as CLEC15B (C-type lectin domain family 15 member B), is a 409 amino acid single-pass membrane protein that contains one C-type lectin domain. Existing as two alternatively spliced isforms, the gene encoding KLRG2 maps to human chromosome 7, which houses over 1,000 genes and comprises nearly 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance. Deletions of portions of the q arm of chromosome 7 are also seen in a number of myeloid disorders including cases of acute myelogenous leukemia and myelodysplasia.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of KLRG2 of human origin by WB, IP, IF and ELISA non cross-reactive with KLRG1
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of KLRG2 of human origin
Tissue Specificity
epitope mapping within an internal region of KLRG2 of human origin