UGP2 (UDP-glucose pyrophosphorylase 2), also known as UDPG, UGPP2, UDPGP2 or pHC379, is an evolutionarily conserved protein belonging to the UDPGP type 1 family of proteins. Localizing to the cytoplasm, UGP2 forms homooligomers and is believed to function as a glucosyl donor in cellular metabolic pathways. More specifically, UGP2 catalyzes the transfer of a glucose moiety from glucose-1-phosphate to UTP, producing a diphosphate and UDP-glucose. UDP-glucose is an essential precursor for the synthesis of polysaccharides; in liver and muscle, UDP-glucose is a precursor of glycogen, in liver UDP-glucose is also a precursor of UDP-glucuronate, and in lactating mammary gland UDP-glucose is converted to UDP-galactose and then to lactose.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of UGP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-300 mapping at the N-terminus of UGP2 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-300 mapping at the N-terminus of UGP2 of human origin
Western blot analysis of UGP2 expression in mouse liver tissue extract.
Application Notes
recommended for detection of UGP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine, porcine and avian
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.