Application
Western blot analysis of 2410091C18Rik expression in non-transfected: (A) and mouse 2410091C18Rik transfected: (B) 293T whole cell lysates.| Product Name | C2orf56 Antibody (Y-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | C12orf56 (chromosome 12 open reading frame 56), also known as PRO1853 or protein midA homolog, is a 441 amino acid mitochondrial protein that belongs to the midA family. Existing as two alternatively spliced isoforms, C12orf56 is encoded by a gene that maps to human chromosome 2p22.2. As the second largest human chromosome, chromosome 2 makes up approximately 8% of the human genome and contains 237 million bases encoding over 1,400 genes. A number of genetic diseases are linked to genes on chromosome 2. Harlequin icthyosis, a rare skin deformity, is associated with mutations in the ABCA12 gene. The lipid metabolic disorder sitosterolemia is associated with ABCG5 and ABCG8. An extremely rare recessive genetic disorder, Alström syndrome, is related to mutations in the ALMS1 gene. Chromosome 2 contains a probable vestigial second centromere as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of C2orf56 of human origin, 2410091C18Rik of mouse origin and the corresponding rat homolog by WB, IP, IF and ELISA non cross-reactive with other C2orf family members also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of C2orf56 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of C2orf56 of human origin |
| Entrez Gene | 55471 |
|---|
Application
Western blot analysis of 2410091C18Rik expression in non-transfected: (A) and mouse 2410091C18Rik transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of C2orf56 of human origin, 2410091C18Rik of mouse origin and the corresponding rat homolog by WB, IP, IF and ELISA non cross-reactive with other C2orf family members also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
