| Modification Notes |
ARMCX5 (armadillo repeat containing, X-linked 5) is a 558 amino acid protein that contains three ARM repeats and is encoded by a gene that maps to human chromosome Xq22.1. Chromosome X consists of nearly 153 million base pairs encoding approximately 1,000 genes. More than one copy of the X chromosome with a Y chromosome causes Klinefelter's syndrome. A single copy of X alone leads to Turner's syndrome. More than 2 copies of the X chromosome, in the absence of a Y chromosome, is known as Triple X syndrome. Color blindness, hemophilia and Duchenne muscular dystrophy are X chromosome-linked conditions that affect males more frequently because males carry a single X chromosome. |