| Product Name | Limkain b1 Antibody (E-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of Limkain b1 of human origin |
| Modification Notes | Limkain b1 (LKAP), also known as KIAA0430 or 4921513D23Rik, is a 1741 amino acid protein that localizes to the peroxisome. Limkain b1 has been found to interact with LIMK-2, a protein that may be important for cell fate determination and growth control. Limkain b1 contains one RRM (RNA recognition motif) domain, indicating that Limkain b1 may bind single-stranded RNA. Limkain b1 is expressed as six isoforms produced by alternative splicing events. The gene that encodes Limkain b1 maps to human chromosome 16, which encodes over 900 genes in approximately 90 million base pairs, making up nearly 3% of human cellular DNA. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Limkain b1 of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of Limkain b1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of Limkain b1 of human origin |
| Entrez Gene | 9665 |
|---|
| Application Notes | recommended for detection of Limkain b1 of human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
