Application
Western blot analysis of FOXJ1 expression in non-transfected: (A) and human FOXJ1 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of FOXJ1 expression in non-transfected: (A) and human FOXJ1 transfected: (B) 293T whole cell lysates.| Product Name | FOXJ1 Antibody (H-201) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Forkhead-box J1 (FOXJ1) is a 421-amino acid transcription factor that suppresses T cell activity and thus spontaneous autoimmunity, through the repression of NF˚B activity. FOXJ1 also inhibits the humoral immune response in B cells; FOXJ1 deficiency in B cells results in spontaneous and accentuated germinal center formation, implicated in the development of pathogenic autoantibodies and accentuated responses to immunizations. Abnormal expression of FOXJ1 may be associated with autoimmune diseases and/or other inflammatory diseases. FOXJ1 is also required for cilia formation and left-right axis determination because it increases calpastatin expression, a protein necessary for the ability of basal bodies to anchor to the apical cytoskeleton. FOXJ1 expression may function as an early marker of epithelial cell differentiation, recovery, and function. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FOXJ1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 221-421 mapping at the C-terminus of FOXJ1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 221-421 mapping at the C-terminus of FOXJ1 of human origin |
| Entrez Gene | 2302 |
|---|
Application
Western blot analysis of FOXJ1 expression in non-transfected: (A) and human FOXJ1 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of FOXJ1 expression in non-transfected: (A) and human FOXJ1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of FOXJ1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
