| Product Name | CPVL Antibody (H-47) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Carboxypeptidases function as proteases and cleave single amino acids from the C-terminus of peptides or proteins. There are three main groups of carboxypeptidases, namely serine-, cysteine- and metallo-enzymes. CPVL (carboxypeptidase, vitellogenic-like), also known as HVLP (VCP-like protein), is a serine carboxypeptidase that is similar to the vitellogenc carboxypeptidase found in mosquito ovaries. Belonging to the peptidase S10 family, CPVL is expressed in myeloid cells of the immune system and is also found in spleen, kidneys, placenta and heart. CPVL contains four putative N-glycosylation sites and a serine carboxypeptidase active site. During monocyte maturation into macrophages, CPVL expression is induced. This suggests a possible role for CPVL in phagocytosis, antigen processing and organization of the innate immune response. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CPVL of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 147-193 mapping within an internal region of CPVL of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 147-193 mapping within an internal region of CPVL of human origin |
| Entrez Gene | 54504 |
|---|
| Application Notes | recommended for detection of CPVL of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
