The bromodomain-containing proteins include BRD2, BRD3, BRD4 and BRDT. BRD2 (RING3 protein) is a mitogen-activated nuclear protein whose gene is located in the human MHC II region, suggesting its relation to HLA-associated diseases. The gene encoding BRD3 (RING3-like protein) contains 2 bromodomains and the gene encoding for the protein maps to chromosome 9q34. BRD4 (HUNK1 protein) is a nuclear protein involved in the regulation of chromosomal dynamics during mitosis. The testis-specific bromodomain protein BRDT contains a PEST sequence, indicating that it undergoes rapid intracellular degradation. The bromodomain-containing proteins proteins are ubiquitously expressed.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of BRDT of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and bovine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 820-851 mapping near the C-terminus of BRDT of human origin
Tissue Specificity
epitope corresponding to amino acids 820-851 mapping near the C-terminus of BRDT of human origin
recommended for detection of BRDT of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and bovine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.