| Product Name | Aspartoacylase-3 Antibody (M-164) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 21-184 mapping near the N-terminus of Aspartoacylase-3 of mouse origin |
| Modification Notes | Aspartoacylase-3 (ACY3), also known as aminoacylase-3, Aspartoacylase-2, acylase III or HCBP1 (Hepatitis C virus core-binding protein 1), is a 319 amino acid protein that deacetylates mercapturic acids in the proximal tubules of the kidney, where it is predominantly expressed. A member of the aspA/astE family and Aspartoacylase subfamily, Aspartoacylase-3 localizes to the cytoplasm of S2 and S3 proximal tubules and to the apical domain of S1 proximal tubules. Aspartoacylase-3 is also expressed at low levels in stomach, testis, heart, brain, lung and liver, and may function as an HCV (Hepatitis C virus) core binding protein. Aspartoacylase-3 is encoded by a gene that maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Aspartoacylase-3 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 21-184 mapping near the N-terminus of Aspartoacylase-3 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 21-184 mapping near the N-terminus of Aspartoacylase-3 of mouse origin |
| Application Notes | recommended for detection of Aspartoacylase-3 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
