| Product Name | CHD1 Antibody (H-210) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1500-1709 mapping at the C-terminus of CHD1 of human origin |
| Modification Notes | Chromodomains participate in the recognition of lysine-methylated histone tails and nucleic acids. The CHD1 protein, named for its chromo-domain, ATPase helicase-like domain and DNA-binding domain, functions as an ATP-utilizing chromatin assembly factor. Unlike HP1 and Polycomb proteins that use single chromodomains to bind to their respective methylated Histone H3 tails, the two chromodomains of CHD1 cooperate to associate with one methylated H3 tail. Unique inserts within chromodomain 1 of CHD1 block the expected site of H3 tail binding seen in HP1 and Polycomb, and instead direct H3 binding to a groove at the interchromodomain junction. The human CHD1 gene maps to 5q21.1, and encodes a 1,709 amino acid deduced protein that shares 95.5% identity with the 1,711 amino acid mouse Chd1 polypeptide. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CHD1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1500-1709 mapping at the C-terminus of CHD1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1500-1709 mapping at the C-terminus of CHD1 of human origin |
| Entrez Gene | 1105 |
|---|
| Application Notes | recommended for detection of CHD1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
