| Product Name | ACSL5 Antibody (H-41) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Acyl-CoA synthetases, also known as long-chain fatty-acid CoA synthases (FACL) or palmitoyl-CoA ligases, include ACSL1-6, which are all single-pass membrane proteins localizing to the mitochondrion, microsome or peroxisome. ACSL proteins are important for synthesis of cellular lipids and for ∫-oxidation degradation. Specifically, ACSL proteins catalyze the activation of long-chain fatty acids to acyl-CoAs, which can be metabolized to form CO2, triacylglycerol (TAG), phospholipids (PL) and cholesteryl esters (CE). ACSL5 utilizes a wide range of saturated fatty acids with a preference for C16-C18 unsaturated fatty acids. It is highly expressed in uterus and spleen. A decrease in expression of ACSL5 is correlated with tumorigenesis, including endometrioid adenocarcinomas and colorectal carcinomas. ACSL5 is also useful as a differentiating marker in the gastrointestinal tract. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of short isoform and long isoform of ACSL5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-41 mapping at the N-terminus of ACSL5 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-41 mapping at the N-terminus of ACSL5 of human origin |
| Entrez Gene | 51703 |
|---|
| Application Notes | recommended for detection of short isoform and long isoform of ACSL5 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
