Application
Western blot analysis of Stabilin-1 expression in Daudi whole cell lysate.| Product Name | Stabilin-1 Antibody (H-193) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1202-1394 mapping within an internal region of Stabilin-1 of human origin |
| Modification Notes | Stabilin-1 (also known as MS-1 antigen or FEEL1) is a large, transmembrane receptor protein that is involved in cell adhesion, angiogenesis, lymphocyte homing and receptor scavenging. It may also be involved in defense against bacterial infections by binding to both Gram-positive and Gram-negative bacteria. Stabilin-1 is primarily expressed on sinusoidal endothelial cells of liver, spleen, lymph node and placenta. It contains tandem fasciclin domains, epidermal growth factor-like repeats and a C-type lectin-like hyaluronan-binding Link module, which functions as an endocytic receptor for acetylated low density lipoprotein and advanced glycation end products. Stabilin-1 has also been reported to mediate both homing of leukocytes across lymph node high endothelial venules and adhesion of metastatic tumor cells to peritumoral lymphatic vessels. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Stabilin-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1202-1394 mapping within an internal region of Stabilin-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1202-1394 mapping within an internal region of Stabilin-1 of human origin |
Application
Western blot analysis of Stabilin-1 expression in Daudi whole cell lysate.| Application Notes | recommended for detection of Stabilin-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
