Application
Western blot analysis of BCAM expression in K-562 (A), TF-1 (B) and MIA PaCa-2 (C) whole cell lysates.Application
Western blot analysis of BCAM expression in non-transfected: (A) and mouse BCAM transfected: (B) 293T whole cell lysates.Application
Western blot analysis of BCAM expression in non-transfected: (A) and human BCAM transfected: (B) 293T whole cell lysates.| Product Name | BCAM Antibody (H-44) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 258-301 mapping within an internal region of BCAM of human origin |
| Modification Notes | Cell adhesion molecules (CAMs) influence cell growth, differentiation, embryogenesis, immune response and cancer metastasis by networking information from the extracellular matrix to the cell. Regulation of neuronal synaptic adhesion by CAMs has proven important for learning and memory. Proper embryonic morphogenic development is also heavily dependent on the regulation of cell adhesion molecules. Mutation of CAM genes has been linked to several forms of cancer, effecting tumor growth and metastasis. Lutheran blood group glycoprotein, also designated B-CAM cell surface glycoprotein or auberger B antigen, plays a role in intracellular signaling. It is a widely expressed protein but the highest level of expression is in pancreas tissue. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BCAM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 258-301 mapping within an internal region of BCAM of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 258-301 mapping within an internal region of BCAM of human origin |
Application
Western blot analysis of BCAM expression in K-562 (A), TF-1 (B) and MIA PaCa-2 (C) whole cell lysates.
Application
Western blot analysis of BCAM expression in non-transfected: (A) and mouse BCAM transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of BCAM expression in non-transfected: (A) and human BCAM transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of BCAM of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
