| Product Name | Kindlin-3 Antibody (T-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of Kindlin-3 of human origin |
| Modification Notes | Kindlin-3, also known as FERMT3 (fermitin family homolog 3), URP2, KIND3, MIG-2, MIG2B or URP2, is a 667 amino acid protein that localizes to both the cell membrane and the cytoplasm and contains one PH domain and one FERM domain. Expressed at high levels in lymph node tissue and at lower levels in spleen, thymus, stomach, placenta, lung, testis and small intestine, Kindlin-3 is thought to be involved in cell adhesion events and may play a role in apoptosis. Kindlin-3 is overexpressed in B-cell malignancies, suggesting that, via its ability to affect cell adhesion, Kindlin-3 may participate in tumor transformation and metastasis. Two isforms of Kindlin-3, designated short and long, exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of Kindlin-3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with Kindlin-1 also reactive with additional species, including equine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of Kindlin-3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of Kindlin-3 of human origin |
| Entrez Gene | 83706 |
|---|
| Application Notes | recommended for detection of Kindlin-3 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with Kindlin-1 also reactive with additional species, including equine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
