Application
Western blot analysis of SFRS17A expression in non-transfected: (A) and human SFRS17A transfected: (B) 293T whole cell lysates.Application
Western blot analysis of SFRS17A expression in non-transfected: (A) and human SFRS17A transfected: (B) 293 whole cell lysates.| Product Name | SFRS17A Antibody (D-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of SFRS17A of human origin |
| Modification Notes | SFRS17A (splicing factor, arginine/serine-rich 17A), also known as XE7, 721P, XE7Y, CCDC133, CXYorf3 or DXYS155E, is a 695 amino acid protein that contains one RRM (RNA recognition motif) domain and localizes to nuclear speckles. Widely expressed with highest expression in lung, heart, brain, liver, kidney, pancreas, skeletal muscle, placenta and activated B-cells, SFRS17A is a subunit of the spliceosome and functions to regulate alternative splice site selection for a variety of mRNA precursors. SFRS17A can also function as a monomer that can interact with ZNF265 and SF2/ASF (both of which are involved in pre-mRNA splicing and transcriptional regulation) via its arg/ser-rich domain. Due to alternative splicing events, SFRS17A is expressed as three different isoforms. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SFRS17A of human origin by WB, IP, IF and ELISA non cross-reactive with isoforms 1,2 or 3) also reactive with additional species, including canine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of SFRS17A of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of SFRS17A of human origin |
| Entrez Gene | 8227 |
|---|
Application
Western blot analysis of SFRS17A expression in non-transfected: (A) and human SFRS17A transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of SFRS17A expression in non-transfected: (A) and human SFRS17A transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of SFRS17A of human origin by WB, IP, IF and ELISA non cross-reactive with isoforms 1,2 or 3) also reactive with additional species, including canine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
