Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing cytoplasmic staining of cells in red and white pulps at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.| Product Name | NDUFV3 Antibody (D-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of NDUFV3 of human origin |
| Modification Notes | Located in the mitochondrial inner membrane, mitochondrial complex I is the first and largest enzyme in the electron transport chain of oxidative phosphorylation. By oxidizing NADH that is produced in the Krebs cycle, this complex utilizes the two electrons to reduce ubiquinone to ubiquinol, thereby initiating the passage of electrons to successive complexes and ultimately leading to the reduction of oxygen to water. Mitochondrial complex I consists of over 40 subunits and is of considerable clinical interest since defects in any one of the subunits can lead to various myopathies and neuropathies. As a subunit of mitochondrial complex I, NDUFV3 (NADH dehydrogenase [ubiquinone] flavoprotein 3), also designated NADH-ubiquinone oxidoreductase 9 kDa subunit or CI-9kD, is a 108 amino acid protein that is believed to not be involved in catalysis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of NDUFV3 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA non cross-reactive with NDUFV1 or NDUFV2 also reactive with additional species, including equine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of NDUFV3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of NDUFV3 of human origin |
| Entrez Gene | 4731 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human spleen tissue showing cytoplasmic staining of cells in red and white pulps at high magnification. Kindly provided by The Swedish Human Protein Atlas (HPA) program.| Application Notes | recommended for detection of NDUFV3 of mouse and human origin by WB, IP, IF, IHC(P) and ELISA non cross-reactive with NDUFV1 or NDUFV2 also reactive with additional species, including equine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
