Application
Western blot analysis of C6ST-1 expression in human skeletal muscle (A), mouse kidney (B) and mouse heart (C) tissue extracts.| Product Name | C6ST-1 Antibody (H-110) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-110 mapping at the N-terminus of C6ST-1 of human origin |
| Modification Notes | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These cytosolic enzymes differ in their tissue distribution and substrate specificities, although the gene structure (number and length of exons) is similar among family members. Sulfotransferases are primarily expressed in liver and adrenal tissues, where they add sulfate to steroids and bile acids. Chondroitin 6-sulfotransferase-1 (C6ST-1) is a 486 amino acid protein that localizes in the Golgi apparatus, where it sulfates both chondroitin and keratan sulfate. C6ST-1 is developmentally regulated in many different tissues, with expression continuing through adulthood in the spleen. When C6ST-1 expression is upregulated, the motility of Schwann cells that guide growing axons through both developmental and injured environments increases. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of C6ST-1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-110 mapping at the N-terminus of C6ST-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-110 mapping at the N-terminus of C6ST-1 of human origin |
| Entrez Gene | 9469 |
|---|
Application
Western blot analysis of C6ST-1 expression in human skeletal muscle (A), mouse kidney (B) and mouse heart (C) tissue extracts.| Application Notes | recommended for detection of C6ST-1 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
