| Product Name | ICK Antibody (M-40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 571-610 mapping near the C-terminus of ICK of mouse origin |
| Conjugation | Agarose |
| Modification | Acetylated |
| Modification Notes | Intestinal cell kinase (ICK), also designated MRK, LCK2, KIAA0936 and MGC46090, is a nuclear Cdc2-related kinase. ICK shares nearly identical N-terminal catalytic domains with male germ cell-associated kinase (MAK), however the C-terminal noncatalytic domain of intestinal cell kinase diverges from that of MAK. The catalytic domain of ICK is also related to mitogen-activated protein kinases (MAPKs) and harbors a corresponding TDY motif, the dual phosphorylation of which activates ICK. The phosphorylation of Tyr 159 in the TDY motif requires ICK autokinase activity, but confers only basal kinase activity; full activation of the protein requires additional phosphorylation of Thr 157 in the TDY motif. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | ELISAIFIPWB |
| WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|
| Species Reactivity | HumanMouseRat |
| Predicted Reactivity | equine, canine, bovine and porcine |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 571-610 mapping near the C-terminus of ICK of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 571-610 mapping near the C-terminus of ICK of mouse origin |
| Application Notes | WB:1:100~1:500 IP:1:20~1:100 IF:1:20~1:100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
