| Product Name | SEPHS2 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-60 mapping at the N-terminus of SEPHS2 of human origin |
| Modification Notes | SEPHS2 (selenophosphate synthetase 2), also known as SPS2, Selenium donor protein 2 or Selenide water dikinase 2, is a member of the selenophosphate synthetase 1 family of proteins. SEPHS2 is one of two mammalian homologs of the eubacteria selenophosphate synthetase protein SelD. SelD is an enzyme that generates the selenium donor for the biosynthesis of selenocysteine. SEPHS2 has a similar function to SelD and specifically catalyzes the formation of selenophosphate (the active selenium donor) from selenide and ATP. The knockdown of SEPHS2 expression greatly impairs selenoprotein biosynthesis, suggesting that SEPHS2 is the mammalian enzyme responsible for generating the selenium donor and regulating selenoprotein synthesis. In addition, SEPHS2 is itself a selenoprotein, implying that it may also function as an auto-regulator. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SEPHS2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-60 mapping at the N-terminus of SEPHS2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-60 mapping at the N-terminus of SEPHS2 of human origin |
| Entrez Gene | 22928 |
|---|
| Application Notes | recommended for detection of SEPHS2 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
