Application
Immunofluorescence staining of methanol-fixed Hep G2 cells showing nuclear and cytoplasmic localization.| Product Name | ALS Antibody (H-42) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 304-345 mapping within an internal region of ALS of human origin |
| Modification Notes | The Insulin-like growth factor binding proteins, or IGFBPs, are a family of seven proteins that have co-evolved with the IGFs. IGFBPs serve as shuttle molecules for both IGF-I and IGF-II and confer a level of regulation to the IGF signaling system by influencing the bio-availability, concentration and distribution of IGFs in the extracellular environment. In human circulation, the IGF-binging protein complex requires ALS (IGFBP acid-labile subunit), an extracellular protein involved in receptor-ligand binding and cell adhesion. ALS, detected primarily in plasma, is involved in protein-protein interactions that result in the formation of protein complexes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ALS of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 304-345 mapping within an internal region of ALS of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 304-345 mapping within an internal region of ALS of human origin |
Application
Immunofluorescence staining of methanol-fixed Hep G2 cells showing nuclear and cytoplasmic localization.| Application Notes | recommended for detection of ALS of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
