Application
Western blot analysis of IgD chain C expression in CCRF-CEM (A) and Ramos (B) whole cell lysates.| Product Name | IgD chain C Antibody (H-67) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 284-350 mapping near the C-terminus of IgD Chain C of human origin |
| Modification Notes | IgD chain C (Ig delta chain C region) is an allelic product of the human IGHD gene. The two known IGHD alleles, IGHD*01 and IGHD*02, respectively produce isoforms 1, a secreted protein, and 2, a single-pass type I membrane protein. A member of the adaptive immune system, IgD antibodies are monomers expressed by activated B cells. Containing 3 Ig-like (immunoglobulin-like) domains, IgD chain C is located on chromosome 14 within the human heavy chain locus, lying on the 3’ side of the IgM chain C region from the V-D-J cassette. Polyadenylation at certain sites along the heavy chain locus likely effects the mechanism that determines the alternative splicing event which results in the expression of either IgD chain C or IgM chain C. Some studies have suggested that antigenic coactivation of IgD+ B cells can have a negative influence on bone resorption during infectious events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IgD Chain C of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 284-350 mapping near the C-terminus of IgD Chain C of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 284-350 mapping near the C-terminus of IgD Chain C of human origin |
| Entrez Gene | 3495 |
|---|
Application
Western blot analysis of IgD chain C expression in CCRF-CEM (A) and Ramos (B) whole cell lysates.| Application Notes | recommended for detection of IgD Chain C of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
