| Product Name | CD53 Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 100-219 mapping at the C-terminus of CD53 of human origin |
| Modification Notes | The CD53 antigen is a member of the tetraspanin membrane protein family that is expressed in the lymphoid-myeloid lineage. The tetraspanin superfamily (CD9, CD37, CD53, CD63, CD81 and CD82) comprises a group of cell-surface proteins that are involved in cell activation and signal transduction as well as in cell adhesion, motility and metastasis. Tetraspanin transmembrane proteins have a metastasis suppressor effect by acting as cell motility brakes in tumor cells. Human neutrophils express high levels of CD53, an N-glycosylated pan-leukocyte antigen and the true homolog of the rat MRC-OX-44 antigen. CD53 is expressed on B cells, monocytes, macrophages, neutrophils, single (CD4 or CD8) positive thymocytes and peripheral T cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CD53 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 100-219 mapping at the C-terminus of CD53 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 100-219 mapping at the C-terminus of CD53 of human origin |
| Entrez Gene | 963 |
|---|
| Application Notes | recommended for detection of CD53 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
