| Product Name | LRRC4 Antibody (H-68) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 458-525 mapping within an internal region of LRRC4 of human origin |
| Modification Notes | The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. The primary function of these motifs is to provide a versatile structural framework to mediate the formation of protein-protein interactions. The leucine-rich repeat-containing protein 4 (LRRC4), also designated Brain tumor-associated protein BAG, Nasopharyngeal carcinoma-associated gene 14 protein (NAG14) or Netrin-G2 ligand (NGL-2), contains 1 Ig-like (immunoglobulin-like) domain and 9 LRR (leucine-rich) repeats. LRRC4 is specifically expressed in brain. Methylation of the LRRC4 gene occurs frequently in gliomas, making LRRC4 a biomarker for diagnosis or a potential therapeutic target. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LRRC4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 458-525 mapping within an internal region of LRRC4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 458-525 mapping within an internal region of LRRC4 of human origin |
| Application Notes | recommended for detection of LRRC4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
