| Product Name | Bcl-G Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Bcl-G of human origin |
| Modification Notes | Apoptosis is defined as a set of cascades which, when initiated, program the cell to undergo lethal changes such as membrane blebbing, mitochondrial breakdown and DNA fragmentation. Bcl-2 is one of many key regulators of apoptosis that are essential for proper development, tissue homeostasis and protection against foreign pathogens. Bcl-G, also known as BCL2L14 (BCL2-like 14) or BCLG, is a 327 amino acid cytoplasmic protein that belongs to the Bcl-2 family of apoptosis-regulating proteins. Bcl-G is expressed as three alternatively spliced transcripts designated short, medium and long. The short isoform is testis-specific and localizes to cytosolic organelles, while the long isoform is widely expressed and is distributed throughout the cytosol. Overexpression of Bcl-G induces apoptosis in cells, suggesting a possible role for Bcl-G in tumor suppression. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Bcl-G of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Bcl-G of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of Bcl-G of human origin |
| Entrez Gene | 79370 |
|---|
| Application Notes | recommended for detection of Bcl-G of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
