epitope mapping within an internal region of ZNF279 of human origin
Modification Notes
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. As a member of the krueppel C2H2-type zinc-finger protein family, ZNF279 (zinc finger protein 279), also known as ZNF280B, SUHW2 and ZNF632, is a 543 amino acid nuclear protein that contains four C2H2-type zinc fingers and may function as a transcription factor. ZNF279 is encoded by a gene located on human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of ZNF279 of human origin by WB, IP, IF and ELISA non cross-reactive with other ZNF family members:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of ZNF279 of human origin
Tissue Specificity
epitope mapping within an internal region of ZNF279 of human origin