| Modification Notes |
TCP10L (TCP10-like), also known as PRED77 or TCP10A-2 (T-complex protein 10A-2), is a 215 amino acid protein that contains a 25-amino acid leucine zipper motif and belongs to the TCP10 family. Localized to the nucleus and expressed specifically in testis and liver, TCP10L is thought to function as a transcriptional repressor that, through its leucine zipper domain, inhibits the expression of a variety of reporter genes. Additionally, TCP10L interacts with proteins such as Mad 4 and ZIP-kinase (also known as DAPK-3) and, through these interactions, may mediate both spermatogenesis and the level of differentiation in liver cells. |