Application
Western blot analysis of COQ9 expression in non-transfected: (A) and human COQ9 transfected: (B) 293T whole cell lysates.| Product Name | COQ9 Antibody (H-154) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 165-318 mapping at the C-terminus of COQ9 of human origin |
| Modification Notes | Coenzyme Q (COQ), also referred to as ubiquinone, is a fat-soluble component of the electron transport chain that participates in aerobic cellular respiration within mitochondria and is essential for ATP-dependent energy production. COQ9 (coenzyme Q9 homolog) is a 318 amino acid protein that localizes to the mitochondrion and is involved in the synthesis of coenzyme Q. Multiple isoforms of COQ9 exist due to alternative splicing events. The gene encoding COQ9 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of COQ9 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 165-318 mapping at the C-terminus of COQ9 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 165-318 mapping at the C-terminus of COQ9 of human origin |
| Entrez Gene | 57017 |
|---|
Application
Western blot analysis of COQ9 expression in non-transfected: (A) and human COQ9 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of COQ9 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
