epitope corresponding to amino acids 1-120 mapping at the N-terminus of TSPY of human origin
Modification Notes
Testis-specific protein Y-encoded (TSPY) is the product of a tandem gene cluster on the human proximal Yp gene. TSPY genes have been conserved and maintained on the mammalian Y chromosome since before the radiation of eutheria, 80 million years ago. TSPY functions as an important factor in cell cycle progression, cell proliferation and tumorigenesis. TSPY may participate in the oncogenesis of gonadoblastoma expression and a variety of other tumor tissues, including testicular germ cell tumors, prostate cancer, melanoma and liver cancer. The Sox family of proteins regulate the expression of TSPY, and its activity is phosphorylation dependent. TSPY may be a potential candidate in vaccine strategy for immunotherapy in hepatocellular carcinoma patients.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TSPY of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-120 mapping at the N-terminus of TSPY of human origin
Tissue Specificity
epitope corresponding to amino acids 1-120 mapping at the N-terminus of TSPY of human origin