| Product Name | FRAS1 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 6-300 mapping within an N-terminal extracellular domain of FRAS1 of human origin |
| Modification Notes | Extracellular matrix protein FRAS1 is a 4007 amino acid protein belonging to the FRAS1 family. Expressed in many adult tissues, FRAS1 has the highest levels of expression in kidney, pancreas, thalamus, fetal kidney and fetal heart. FRAS1 contains 5 Calx-beta domains, which bind calcium with high affinity and undergo a major conformational shift upon binding. Additionally, it contains 12 CSPG (NG2) repeats, 14 FU (furin-like) repeats and 6 VWFC domains. Mutations in the gene encoding FRAS1 cause Fraser syndrome, a multisystem malformation usually comprising cryptophthalmos, cutaneous syndactyly, ear abnormalities, renal agenesis and congenital heart defects. Five named isoforms of FRAS1 exist as a result of alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FRAS1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 6-300 mapping within an N-terminal extracellular domain of FRAS1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 6-300 mapping within an N-terminal extracellular domain of FRAS1 of human origin |
| Entrez Gene | 80144 |
|---|
| Application Notes | recommended for detection of FRAS1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
