| Product Name | HS6ST2 Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 141-230 mapping within an internal region of HS6ST2 of human origin |
| Modification Notes | HSPGs (heparan sulfate proteoglycans) are long chains of HSs (heparan sulfates) which are connected to core proteins and are expressed ubiquitously on cell surfaces. HSs are thought to interact with many proteins including growth factors, morphogens and their receptors whose functions include the regulation of ligand stability. In the Golgi apparatus, HS structures are thought to be synthesized by heparan-sulfate chain modification enzymes. HS6ST2 (heparan sulfate 6-O-sulfotransferase 2), is a 605 amino acid single-pass type II membrane protein that belongs to the sulfotransferase 6 family. HS6ST2 catalyzes the transfer of sulfate from PAPSS to a specific position of the N-sulfoglucosamine residue of HS. It is suggested that the thyroid hormone negatively regulates expression of HS6ST2. Three isoforms exists due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of HS6ST2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 141-230 mapping within an internal region of HS6ST2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 141-230 mapping within an internal region of HS6ST2 of human origin |
| Entrez Gene | 90161 |
|---|
| Application Notes | recommended for detection of HS6ST2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
