| Product Name | Bex4 Antibody (H-49) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 67-115 mapping near the C-terminus of Bex4 of human origin |
| Modification Notes | The brain-expressed X-linked (Bex) family of proteins is expressed in the central nervous system, with highest levels detected in cerebellum, temporal lobe and pituitary tissues. Bex4, also known as Bex1-like 1, TCEAL7 or nerve growth factor receptor-associated protein 3, is a member of the Bex family involved in cell death regulation. It is expressed highly in heart, skeletal muscle and liver localizing to the nucleus and the cytoplasm. Bex4 is frequently downregulated or inactivated by methylation in ovarian tumors and cancer cell lines. Forced expression of Bex4 induces apoptosis and reduces colony formation. This suggests that Bex4 acts as a tumor suppressor. Bex4 shares 50% sequence homology with the apoptosis-inducing domain of Bex3 and 77% sequence homology with its regulatory domain. Bex4 is located on the X chromosome and is subject to X chromosome inactivation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Bex4 of human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 67-115 mapping near the C-terminus of Bex4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 67-115 mapping near the C-terminus of Bex4 of human origin |
| Entrez Gene | 56271 |
|---|
| Application Notes | recommended for detection of Bex4 of human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
