Application
Western blot analysis of RIL expression in SK-N-SH whole cell lysate.| Product Name | RIL Antibody (H-130) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | RIL (reversion-induced LIM protein), also known as PDZ and LIM domain protein 4, is a widely expressed 334 amino acid protein. RIL contains one PDZ(DHR) domain and one LIM zinc-binding domain. The LIM zinc-binding domain interacts with the second and fourth PDZ domains of Fap-1, possibly resulting in the dephosphorylization of RIL. Although an exact function is unknown, RIL expression in human bone marrow stromal cells suggests involvement in osteoblast development and function. Variations in the RIL gene have been shown to have an allelic dose effect on bone mineral density (BMD), with BMD being an important determinant of osteoporosis. RIL exists as two isoforms, with isoform 2 present in the brain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of RIL of mouse, rat and human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 71-200 mapping within an internal region of RIL of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 71-200 mapping within an internal region of RIL of human origin |
| Entrez Gene | 8572 |
|---|
Application
Western blot analysis of RIL expression in SK-N-SH whole cell lysate.| Application Notes | recommended for detection of RIL of mouse, rat and human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
