Application
Western blot analysis of TSKS expression in HL-60 whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic and membrane localization.| Product Name | TSKS Antibody (E-21) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TSKS (testis-specific kinase substrate), also known as STK22S1 and TSKS1, is a 592 amino acid protein that is highly expressed in human testicular tissue. Low levels of TSKS are detectable in prostate, placenta, fetal liver, thymus, and mammary gland tissues. TSKS is found to be downregulated in cancerous testicular tissue from seminoma, teratocarcinoma, embryonal and Leydig cell tumors concurrently with high expression in neighboring premalignant carcinoma. TSKS protein contains an N-terminal signal peptide, but does not contain a transmembrane region. TSKS has many potential phosphorylation and glycosylation sites and is phosphorylated by soluble recombinant TSSK2 in vitro. It is thought that TSKS likely plays a physiological role in spermatogenesis or spermiogenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of TSKS of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of TSKS of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 60385 |
|---|
Application
Western blot analysis of TSKS expression in HL-60 whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human lung carcinoma tissue showing cytoplasmic and membrane localization.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
